The consumption of ultra-processed foods is increasingly earlier, which poses a
greater risk for the development of several chronic non-communicable diseases, so
the objective of this study was to evaluate the introduction of ultra-processed foods in
the diet of children under two years of age. and its associated factors. The work was
constructed in two parts, the first comprising the theoretical framework and the second
comprising field research. For field research, a quantitative cross-sectional study was
used as a methodology, carried out with mothers or caregivers of children under 2
years of age, monitored in basic health units that have multi-professional residences
located in the city of Mossoró/RN. Data collection was carried out on childcare and
vaccination days, where a family socioeconomic and demographic questionnaire and
another questionnaire on the child's food consumption were applied, through which the
presence of consumption of ultra-processed foods and its association with
socioeconomic and demographic characteristics through Poisson regression. Our
sample consisted of 293 mothers or caregivers, of which 97.3% were female, among
the children 52.2% were also female, with an average age of 7.1 months. 53.7% of
children under 6 months were on exclusive breastfeeding and 30.5% were taking
formula, 67.1% of children over 6 months and under 2 years were on continued
breastfeeding and 30.2% of them were consuming porridge the day before the
research. A prevalence of 37.8% of consumption of ultra-processed foods was
identified, and the factors associated with this consumption were lower maternal
education, receipt of financial assistance, receipt of guidance on complementary
feeding and older age of the child. These results highlight the early introduction of ultraprocessed
foods in children under 2 years of age, a practice not recommended for this
age group. The study made it possible to contribute to knowledge about the factors
associated with the introduction of these foods and thus provide data for the
formulation of public policies to strengthen breastfeeding and adequate
complementary feeding.

Introduction: Non-carious lesions (NCLs) are one of the main problems in the oral health of
the population, their clinical signs are as present in the day to day dental clinic as caries. The
formation and progression of these lesions are due to the association of three etiological factors
(tension, friction and biocorrosion) that are added to risk factors, such as health literacy, level
of education and socioeconomic factors are related to disease progression in populations of
different age groups. Objective: To evaluate the relationship between the prevalence of noncarious
lesions, educational level and oral health knowledge. Methodology: This is an
analytical study, cross-sectional, quantitative, with patients under dental care in the Dentistry
School-Clinics of the University of Rio Grande do Norte, Caicó/RN campus. Patients answered
questionnaires on sociodemographic data and on access and use of health services. To evaluate
the level of Oral Health Literacy (OHL), the Brazilian Rapid Estimate of Adult Literacy in
Dentistry (BREALD-30) was applied, which makes it possible to classify knowledge at a low
level of literacy (score ≤ 21 points), moderate level (ranging from 22 to 25 points) or high level
(score ≥ 26 points). For diagnosis and classification of NCLs patients underwent clinical
examination, which followed the criteria of Smith and Knight, 1984. Results: The final sample
consisted of 62 patients. The prevalence found for NCL was 96.8% (n=60), with 48.4% (n=30)
of the lesions located on the incisal face and 41.9% (n=26) on the cervical face. Wear on the
incisal face was more present in the population between 18 and 30 years (n=14), while wear on
the cervical face was more present in the population between 41 and 50 years (n=10). The
prevalence of score 2 was higher for the age group 41 to 50 years, with 34.4% (n=11), while
the prevalence for grade 3, was higher for the age group 51 to 60 years, with 37.5% (n=6) and
grade 4, for the age group above 61 years, with 50% (n=2). A majority of 51.6% of the research
participants have a high level of OHL, 30.7% have a low level of knowledge, while 17.7% have
a moderate level. Fisher’s exact test showed an association between NCL and income
(p=0.032), NCL and schooling (p=0.038). The injury score was associated with age group
(p=0.003), position that the member exercises in the family (p=0.047) and education (p=0.033).
There was an association between OHL levels and age (p=0.024), self-reported race (p=0.002),
socioeconomic status (p=0.004) and schooling (p=0.001). There was also significance between
OHL and the need for current dental treatment (p=0.027), and place of the last visit (p = 0.008).
The Chi-square test of independence showed that there is an association between the OHL and
the reason for the last visit to the dentist (p=0.024). Conclusions: The study showed a significant relationship between the prevalence of non-carious lesions, with high level of oral
health literacy, high socioeconomic status and high level of education.

Objective: To evaluate, in vitro, the erosive potential of energy drinks modified by different variations and concentrations of calcium on dental enamel. Methodology: This is an in vitro study in which 60 specimens of healthy human dental enamel were used. Initially, all specimens had their surface roughness (Ra and Rz1max) and microhardness measured using a rugosimeter and a Vickers microhardness tester, respectively. Subsequently, they were divided into three groups and 12 subgroups (five per subgroup) to be exposed to the tested beverages, which were as follows: Experimental group (G1 to G9 – Red Bull® traditional energy drink modified with concentrations of 0.71, 1.43, and 2.15 grams of the calcium/phosphorus/potassium complex; 0.83, 1.66, and 2.50 grams of dicalcium malate; and 1.26, 2.53, and 3.80 grams of calcium citrate malate, respectively); negative control group (G10 – Traditional Red Bull® energy drink and G11 – Deionized water); and positive control group (G12 – Low-Calorie Life Mix Orange Juice® supplemented with calcium). The pH of all beverages was measured using a calibrated pH meter with a pH electrode. After preparing all the beverages, the specimens were exposed to them for two minutes. Finally, their surface roughness (Ra and Rz1max) and microhardness were reevaluated. For statistical analysis, the Kruskal-Wallis, Mann-Whitney, and Wilcoxon tests were applied, adopting a significance level of 5%. Results: Regarding the pH behavior of the beverages, modifications to the energy drink with concentrations of the calcium/phosphorus/potassium complex increased its pH concurrently with the substance concentration. As for the analysis of specimen roughness, the experimental group showed a significant difference (p < 0.004) compared to subgroups G10, G11, and G12 for the Ra and Rz1max parameters. In the evaluation of specimen microhardness, significant differences (p < 0.004) were observed between subgroups: G3-G10, G6-G10, and G10-G11. All specimens exposed to the beverages in the experimental group had a lower percentage of enamel surface hardness loss compared to those exposed to subgroups G10 and G12. Conclusion: The calcium variations added to the energy drink demonstrated effectiveness in reducing the erosive potential of this type of beverage at all tested concentrations on dental enamel, with better performance observed for the calcium/phosphorus/potassium complex.

Introduction: Chagas disease is a neglected illness that manifests in indeterminate, cardiac, digestive, and cardio-digestive clinical forms. In Brazil, an estimated 3.2 million cases were reported in 2020. In this context, nurses play a crucial role in care, with Nursing Care Systematization being an essential tool. Scientific literature on nursing care for individuals with Chagas disease, especially focusing on Nursing Diagnoses, is scarce. Objectives: To identify the main Nursing Diagnoses present among individuals with Chronic Chagas Disease treated at the Chagas Disease Outpatient Clinic of the State University of Rio Grande do Norte (ADOC/UERN); to examine the association between Nursing Diagnoses and sociodemographic variables and lifestyle habits; and to assess the association between Nursing Diagnoses and clinical variables and aspects of self-care. Materials and methods: A cross-sectional and descriptive study with a quantitative approach was conducted in the Western Potiguar Mesoregion. The research took place at ADOC/UERN, which averages 162 appointments per year. After calculation, the sample consisted of 96 individuals with chronic Chagas disease. Nursing consultations were conducted using a data collection instrument and following Orem's Theory, including history-taking and physical examination. Nursing Diagnoses were determined based on the 12th edition of NANDA–I Nursing Diagnoses. The analysis involved descriptive statistics and statistical tests such as Pearson's chi-square and Fisher's exact test. The research was approved by the Research Ethics Committee of the State University of Rio Grande do Norte. Results: The main Nursing Diagnoses identified were Sedentary Lifestyle, Risk for Impaired Cardiovascular Function, and Deficient Knowledge. Sociodemographic and clinical variables were statistically associated with Nursing Diagnoses such as Risk for Impaired Cardiovascular Function, Impaired Swallowing, Overweight, Decreased Engagement in Leisure Activities, Impaired Urinary Elimination, Risk for Falls in Adults, Anxiety, Insomnia, and Deficient Knowledge. Discussion: Nursing Diagnoses emphasize the need to expand care beyond the physiological characteristics of the disease, identifying specific care for patients despite different contexts. There is an urgency to reconsider knowledge-building processes, promoting the inclusion of Chagas disease in health undergraduate courses, especially in endemic regions. Additionally, investing in continuous education for healthcare professionals and health education programs is essential to enhance knowledge about the disease, its cardiovascular risks, necessary lifestyle changes, and to promote self-care for affected individuals and their caregivers. Conclusion: The Nursing Diagnoses in this study address not only the clinical aspects of Chagas disease but also social, physical, behavioral, economic, spiritual, and family factors, crucial for understanding the complexity of the individual. This allows for the development of integrated care plans, highlighting the need for regional and national assistance programs for individuals with chronic diseases, including intervention strategies and health education.

Introduction: The presence of ring neutrophils (NAs) is observed in patients with
chronic inflammatory conditions. Recently, Fractal Dimension (DF) was inserted in the
evaluation of morphological modifications of cells in clinical scenarios, such as cancer;
and applied in the evaluation of neutrophils from healthy individuals, when changes in
nuclear chromatin compatible with different stages of maturation of these cells were
observed. Objective: To investigate the frequency of NAs and to apply FD to detect
chromatin alterations in neutrophils from peripheral blood of patients infected with
Trypanosoma cruzi and/or HIV. Casuistry and Methods: This was a case-control
study. Fifty-three individuals were recruited and divided into four groups: (G1)
Trypanosoma cruzi infected (n=18), (G2) HIV seropositive (SPHIV) (n=14), (G3) T.
cruzi-HIV coinfected (n=09) and (G4) healthy individuals (n=12). Five mL of
peripheral blood were collected for total leukocyte count using a BC-3000 Plus®
automated counter and production of hematological slides. A camera (16 megapixels)
was attached for reading the slides in the optical microscope, and the magnification was
adjusted to 1000x with 75% luminosity. A total of 100 neutrophil micrographs were
recorded per individual, for a total of 5,300 fractal analyses. The images were subjected
to AF by the box-counting method of the "FracLac" plugin of Image JTM software.
Results: The NAs were found in all four groups, in low frequency (less than 5%), with
statistical difference between the healthy and the infected groups (G1, p=0.0250; G2,
p=0.0068; G3, p=0.0009). The morphological findings allowed to divide the NAs into
two subtypes (for all groups): High and low segmentation NAs. In the evaluation of
clinical parameters, the higher the frequency of NAs in peripheral blood: (G1) the
higher the LVMI (p=0.0135) and the risk of ischemic stroke of cardioembolic nature
(p=0.0371); (G2) the higher the CD4+ T lymphocyte count (p=0.0273) and CD8+ T
lymphocyte count (p=0.0030); (G3) the higher CD4+ T count (p=0.0079) and the lower
the LVMI (p=0.0456). The chromatin DF of neutrophils from infected individuals was
lower than that found for the control group (p<0.0001). In the correlational analysis, the
lower the DF, the lower the LVEF (p=0.0066) and the higher the risk of sudden death
(p=0.0052) for chagasic patients (G1). On the other hand, the higher the DF, the higher
CD4+ T counts (p=0.0264) in SPHIV (G2); and the higher the LVEF (0.0219) and CD4+
T counts (p=0.0271) in coinfected (G3). Conclusion: This evidence suggests that
increased NAs confer a worse prognosis on chagasic patients, whereas it has a
protective role in individuals in groups 2 and 3. The DF was an independent marker in
detecting discrete changes in neutrophil nuclear chromatin and proved to be a
prognostic tool and risk stratification for unfavorable events, survival and mortality of
individuals infected with T. cruzi and/or HIV.

Enamel hypomineralization is a qualitative defect that is visually recognized as an area of modification in the translucency of the enamel, which can present itself in a diffuse or demarcated manner. The lesions demarcated in the second primary molars led to the description as Hypomineralised Primary Second Molars - HPSMs. In HPSMs, these qualitative defects of systemic origin occur in at least 1 of the 4 deciduous second molars, and in some cases, other teeth can also be affected, especially the deciduous canines. Objective: To evaluate the possible association between hypomineralization of the deciduous second molar and dental anomalies of second premolars successors. Material and Methods: The sample consisted of 104 orthodontic patients documentation aged between 5 and 12 years, divided into two groups: patients with HPSMs (28) and without HPSMs (76). The HPSMs and other dental anomalies were diagnosed using panoramic radiographs and intraoral photographs. The chi-square test was used to assess intergroup comparison in terms of gender. The chi-square test and Fisher's exact test were used to compare groups in terms of the presence of dental anomalies. Odds Ratios (OR) were calculated to assess the risk of presenting dental abnormalities. Results: There was an association between HPSMs and dental anomalies. Prevalence of dental agenesis of upper second premolars (4.8%), agenesis of lower second premolars (7.7%), mesioangulation of upper second premolars (11.5%), and distoangulation of second premolars lower molars (11.5%) was significantly higher in patients with HPSMs. Individuals with the enamel defect had a chance between 7.2 and 20.6 times greater of presenting the evaluated dental anomalies. Conclusions: HSMD is associated with dental anomalies, especially with agenesis of the upper and lower second premolars.

Introduction: Chagas disease (CD), in its digestive clinical form, is characterized by
the destruction of the myenteric nerve plexuses leading to structural alterations, such as
megacolon, and functional alterations; both associated with nutritional imbalances.
Among the clinical findings, chronic constipation is the main symptom in this group.
Recent evidence suggests that nutritional fiber supplementation may improve the
clinical outcome of these patients. Objectives: To evaluate the effect of dietary
treatment with dietary fiber supplementation in improving the nutritional profile and
chronic constipation in chronic Chagas' patients with clinical digestive form. Methods:
This is a clinical trial with case-crossover design. The research was divided into three
stages: (1) clinical evaluation and nutritional diagnosis; (2) nutritional intervention; and
(3) evaluation. Fifty constipated subjects were submitted to fiber treatment, 30 patients
with CD and 20 patients without CD for the Control Group (CG). We assessed the
anthropometric, laboratory, dietary profile and constipation severity by the Bristol Scale
in the first nutritional consultation (pre-treatment). Dietary intake was assessed by the
24-h recall, while diet quality was analyzed by the Revised Dietary Quality Index (IQDR).
Patients were randomly selected for treatment with 30g of fiber for 45 days. After
the intervention, all variables were reassessed. Results: Prior to fiber supplementation,
the diet of all constipated patients (with CD and without CD) was characterized as
hypercaloric and hyperlipidic. The (IQD-R) showed that the diet quality of all patients
was inadequate before the nutritional intervention (p<0.001). After fiber treatment, in
both groups, significant improvement was seen in all anthropometric parameters
evaluated (p<0.001): weight, BMI, waist circumference and total energy intake. In
addition, there was a significant reduction in blood glucose, triglycerides, total
cholesterol and fractions, and liver transaminases for both groups (p<0.001). Most of
the subjects with CD were classified with severe constipation (type III); and the same
was true for the CG subjects. Fiber treatment significantly improved the IQD-R
(p<0.001) and Bristol Scale (p<0.001) for both groups, relocating most patients to
normal bowel status. Conclusion: In the evaluation of the nutritional, anthropometric
and laboratorial profile, treatment with fibers allowed significant improvement in all
variables for both constipated groups (chagasic and control), but all positive outcomes
were higher in individuals with CD. Fiber treatment was efficient in improving
nutritional status, total or partial resolution of constipation, and adequate emptying of
the colon.

Work stress associated with the daily practice of health workers can trigger a number of problems, often resulting in damage to the health of the worker, with a direct consequence on the quality of the services provided. The sum of the symptoms arising from this condition causes the so-called burnout syndrome (BS), a debilitating state observed in people who experience chronically stressful situations, characterized by a state of emotional exhaustion, depersonalization and lack of fulfillment at work. Among the health professions, nursing is ranked as the fourth most stressful profession. The present study aims to evaluate the risk factors for BS in professional nurses at the Tarcisio de Vasconcelos Maia Regional Hospital in Mossoró/RN. Exploratory, descriptive, prospective, quantitative and cross-sectional study in 119 nurses from March to September 2022, carried out under license from the Research Ethics Committee of UERN (4,915,042). A questionnaire with socio-organizational information and the Copenhagen Burnout Inventory (CBI) containing 19 items that reflect professional burnout, in a scale categorized as low, intermediate and high burnout, were applied. Most of the interviewees were female (81%), with an average of 36.4 years old, married (70%), with specialization in the area (74%), and two jobs (59%). It was possible to identify a higher prevalence of high levels of personal burnout (44%), and intermediate levels of work-related burnout (52%), and client-related burnout (50%). A strong positive correlation between the number of employment contracts for the dimensions personal (r=0.74, p=0.03) and work-related burnout (r=0.81, p=0.02), a strong positive correlation between workload and personal burnout (r=0.68, p=0.04), and a moderate positive correlation between workload and work-related burnout (r=0.53, p=0.04) were identified. Exposure to long workload resulted in increased levels of both physical and psychic exhaustion in nurses, negatively interfering with their professional performance and personal relationships. Future studies focusing on strategies to ensure a better working condition for nurses are needed, seeking approaches aimed at providing better occupational health for workers.

To analyze how nursing professionals identify the patient safety culture in three maternity hospitals. This is a cross-sectional, descriptive, and quantitative study. Data collection was carried out using the validated instrument Hospital Survey on Patient Safety Culture, with nursing professionals from maternity hospitals in the municipalities of Apodi, Pau dos Ferros and Mossoró RN. The sample consisted of 61 professionals. As for the characterization of professionals, most are nursing technicians 57.4%; 90.2% female and 62.5% over 35 years of age. As for length of service, most were from 1 to 5 years (42.1%, 71.4% and 55.5%) and from 20 to 39 hours a week (52.6%, 78.6% and 57 ,1%). The initial hypothesis of the study was confirmed, as the general average of the patient safety culture identified by the nursing professionals at the maternity hospitals was 58.2%, less than 75%. This average is lower than the AHRQ teaching hospital database, which had an average of 63%, and the national survey of Brazilian hospitals, which was 60.2%, above the average for the State of RN, which was 54. 7%. Three dimensions were better evaluated, but only two are strong areas, with a percentage greater than 75%, they were: D1: “Teamwork within the unit” (78.2%) and D2: “Expectations and actions of the supervisor/manager to the promotion of patient safety” (77.8%), followed by D3: “Organizational learning” (68.3%); and as dimensions with weaknesses; and less than 50% had: D12: “Non-punitive responses to errors” (24.7%), D10: “Team” (48.4%) and D5: “General perception of patient safety” (46.8%) %). The question of expectation of supervision obtained an evaluation similar to those found in the AHRQ hospitals, which was 77% and the Brazilian average, which was 78.6%. Still, among the findings, there are differences between the maternity hospitals that may be related to management characteristics, structure and mainly the implementation of security centers; since maternity 3 was the best evaluated, had four strong dimensions, five with neutral areas greater than 50% and two fragile. Hospital 1, on the other hand, was the worst evaluated, as it had no area of strength and eight fragile, in hospital 2 only two positive/strong, seven neutral and three negative/fragile. Based on the findings of this study, it is concluded that the patient safety culture identified by the nursing staff in the maternity hospitals is still configured with important weaknesses, most of the dimensions are at a neutral stage, and few are areas of strength, especially in the service in which professionals have more time working in the maternity ward and in those that do not have a patient safety center implemented; and that linked to this, a punitive view of errors and the existence of a very low adherence to reporting adverse events. As a suggestion, we have the implementation of nuclei in services that it does not yet have, in addition to adapting personnel, engaging the entire multidisciplinary team, training, encouraging learning from mistakes, instead of isolated punitive and corrective actions.

Introduction: The pandemic changed the routine of several people and professionals, printing social isolation and/or intensification of the workload as a measure for the containment of the virus. This need contributed to the development or worsening of mental disorders in the most diverse segments of the population, especially health professionals. Nursing is at the forefront of care in the cases of Covid-19, being more susceptible to infection by the new Corona virus and triggering emotional disorders due to workload. Objectives: To evaluate the impact produced in the Mental Health of Nursing Workers, in view of the pandemic of the corona virus in the municipality of Mossoró-RN. Methodology: Exploratory and descriptive research of quantitative approach where an online questionnaire was applied to nursing professionals who worked in the care of patients with covíd-19. The sample comprised 71 nursing workers. Data analysis was performed using classical statistics, where the P < 0.05 value was established for results with significant relevance for the evaluated hypotheses. Results: 77.5% of the subjects studied were nurses and 22.5% nursing technicians. 19.7% had some emotional disorder before the pandemic, 80.3% did not. Of these, 14.1% reported previous anxiety, stress 1.4%, bulimia 1.4%. Of these, 16.9% undertook psychological follow-up before the pandemic and 83.1% did not. About the diagnosis of mental disorders during the pandemic, 67.6% did not have it, 32.4% did. About the diagnosis, 19.7% anxiety, 1.4% stress, 1.4% panic syndrome, 1.4% burnout and anxiety and 2.8% had all these mental disorders. About the use of psychotropic drugs, before the pandemic, 9.9% made use, 90.1% were not using them. During the pandemic, 23.9% made use and 76.1% did not use it. The variables: socio-demographic profile and comorbidities did not present significant relevance for the emergence of mental disorder diagnoses. Only the workload presented significant relevance for the appointment of emotional diagnoses. The analysis of the signs and symptoms characteristic of anxiety and depression, "difficult to calm", "difficulty breathing", "initiative to do things", "overreaction", "nervousness", "nothing to be desired", "agitated", "difficult to relax", "depression/without mood", "intolerant", "panic", "without enthusiasm", "emotional and sensitive" had a value of P ≤ 0.05, that is, they had significant relevance for the determination of anxiety diagnoses, depression and stress. Conclusion: The reality of the mental health panorama of nursing workers in the face of the Covid-19 pandemic in Mossoró-RN is revealed. One of the most relevant findings was the increase in the number of subjects who started to develop anxiety and, consequently, the use of psychotropic medications to combat these conditions.

INTRODUCTION: Non-carious cervical lesions (NCCL) are among the most frequent situations that affect dental structures. The definition of etiological factors is necessary before selecting treatment strategies for NCCL and also for other conditions that may be associated, such as cervical dentin hypersensitivity. OBJECTIVE: To assess the knowledge of undergraduate students and dentists about diagnosis and treatment for NCCLs, as well as their conduct during the clinical approach to these lesions. METHODOLOGY: This research is descriptive, cross-sectional, exploratory and quantitative in nature. The population of the present study is composed of dental surgeons, aged over 18 years, working in Rio Grande do Norte. It is being carried out in a virtual environment. In this sense, a link with the research questionnaire and its respective informed consent form (TCLE) were sent by email and published on social networks and in message groups in order to reach the desired population. The questionnaire is divided into two parts, the socio-educational part and the second part with information on the level of knowledge about LCNC. The results obtained were organized in a computerized database with the aid of the statistical program SPSS (Statistical Package for the Social Sciences) in version 20.0, and submitted to a descriptive and inferential analysis, with a significance level of 5%. To date, a total of 177 forms have been answered. All answered by dentists, with 47% (84) of the interviewees trained in federal universities, 27% (48) in private colleges and 25% (45) in state colleges. Of the total, 65% (105) of the participants reported being satisfied with their level of knowledge about the diagnosis of LCNC, but that they need to update themselves on the subject. Regarding the clinical routine, 51%(91) of the participants reported that 4 to 6 patients out of 10 have at least one cervical lesion. Regarding the restorative material that the participants deem to be the most suitable for the treatment of CNCL, Composite resin was chosen by 77% (137). FINAL CONSIDERATIONS: So far, with partial data, it is possible to perceive a gap in the knowledge of this population regarding cervical injuries. In addition, he also noted that, due to the prevalence of these injuries, especially in premolars, it is necessary to invest in more prevention strategies and improvement of treatments.

Movement behaviors coincide and reflect in parallel in the health and well-being of
schoolchildren. In the descriptive study of epidemiological profile, this study aimed to
analyze the relationship between 24-hour movement behavior and anthropometric
indicators of 526 students of both sexes aged between 11 and 17 years enrolled in
the public school system of the city of Mossoró/RN. As a data collection instrument,
the adapted Build Your Best Day Questionnaire (physical activity and sedentary
behavior, hours of sleep) and the Xiaomi Mi Band 5 accelerometer were® used to
measure physical activity level and sleep time and Sanny adipometer (skinfolds). It
was observed that from the questionnaire that only 11.98% of the students met the
recommendations of PA completely (moderate/vigorous and mild), 33.84% did not
attend MVPA and 85.36% did not meet the AFL, only 11.03% attend ed if they
attended sedentary behavior and 68.44% did not attend sleep hours, and only
12.61% of the students met the PA recommendation and 80.18% did not meet the
hours of sleep, it is evident that most boys reached the guidelines of movement
behavior. Among girls, lower results were observed in all variables, especially in the
levels of physical activity In relation to the percentage of body fat, 54.18% of the
students were above the limit recommended by Lohman, where 60.39% of the boys
presented a percentage of fat considered an optimal level= and 48.34% of the female
group presented adequate fat percentage. The results indicate that although the
male group presented a higher level of physical activity than girls, most of the
students evaluated did not meet health recommendations, regarding the level of
physical activity, sleep duration and sedentary behavior.

Introduction: The external Globus Pallidus (GPe) is a structure of fundamental importance for the execution of motor activities. The marmoset (Callithrix jacchus) is a new world primate, an animal model of interest for studies in several areas, including neuroscience. The existence of several parallels between marmosets and other mammals points to a demand for investigations involving the cytoarchitecture of the GPe and its relations with the other nuclear structures of the CNS. Objective: To analyze the laminar distribution and morphology of neurons with calcium-binding proteins (calbidin and parvalbumin) in the GPe of marmosets. Methodology: This study will use microscope slides already processed from six young adult male animals will be used. The slides used in the present study were obtained according to the procedures described in the literature, with perfusion, brain extraction, microtomy and Nissl staining and immunohistochemistry for Calbidin (CB) and Parvalbumin (PV). The sections corresponding to the GPe region will be examined by microscopy. Data will be described according to indirect observation and use of descriptive statistics and inferential analysis techniques. Results: IR-CB didn’t revealed cells of any nature in the body of the GPe in both cerebral hemispheres. The parts that presented CB-reactive neurons were confined to the fibers of the middle medullary lamina (MML) and lateral medullary lamina (LML). It was find out that the markings of the GPe and GPi presents more intense colors when these structures are submitted to IR-CB, and the origin of this fact and its implications for the functioning of the GPe it wasn’t yet documented in the literature. Both neurons and fibers containing PV appeared to be distributed along the entire length of the GPe. The PV-immunoreactive neurons have varying size, being multipolar or fusiform, with a thick and well-distributed dendritic structure. Conclusion: The present study evidences the presence of a high number of neurons that show immunoreactivity to PV in the body of the GPe. The distribution of dendritic ramifications marked by the PV also suggests that the neurons documented in this study receive signals from collateral cells containing PV. This study indicates that the neurons that present PV organize themselves to compose a population of GABAergic neurons.

Food Insecurity is characterized by the feeling of concern and/or anguish in the face
of the uncertainty of daily food availability, living with hunger or eating a diet of low
nutritional quality, monotonous and insufficient to meet the basic needs of the
individual. The objective of this study was to verify the association between
household food insecurity and socioeconomic, demographic, anthropometric
variables and food consumption in elementary school students from the public school
system in Mossoró-RN. This is a descriptive study with a cross-sectional
epidemiological design with 267 schoolchildren (municipal schools n=145; state
schools n=122), aged 6 to 12 years, of both sexes, and their families. As research
instruments, a socioeconomic questionnaire, the Brazilian Food Insecurity Scale, the
Food Consumption Marker form from the Ministry of Health, an Onhom scale and a
portable stadiometer from Avanutri were used. Multinomial logistic regression was
used to calculate the odds ratio (OR) and its 95% confidence intervals (CI) for the
categories of security (baseline) and food insecurity (mild and moderate to severe).
The prevalence of food insecurity was 77.5% (mild: 46.4% (95% CI 40.4; 52.8) and
moderate/severe: 31.1% (95% CI 25.5; 37.1 It was observed that families with per
capita income of up to ½ minimum wage and up to 1 minimum wage are more likely
to have mild food insecurity (RC = 2.80, 95% CI 1.24; 6.33; and RC = 3 .27, 95% CI
1.54; 6.94) and moderate to severe food insecurity (OR = 15.63, 95% CI 5.22; 46.79;
and OR = 12.14, 95% CI 4, 14; 35.56) compared families with per capita income
greater than 1 minimum wage. In addition, being a girl and the head of the family
being a woman, as well as being responsible for the child having completed
elementary/secondary education, presenting conditions of poverty and the child not
consuming the three main meals of the day were associated with moderate to severe
food insecurity. emphasis on gender issue.

Sars-Cov 2 evolved into a pandemic from March 2020, through the WHO Decree
and, since then, it has become an increasing problem, with several containment
measures being carried out. Even so, many people were hospitalized due to the
disease and its secondary factors, making it necessary to create a rehabilitation
program for survivors who had sequelae. This is a descriptive study with a crosssectional
cohort that aimed to analyze the physical fitness and quality of life of
individuals infected with Covid-19, submitted to an exercise-based physical
rehabilitation program. The sample included 28 individuals of both sexes, over 18
years old; with hospital discharge; with previous clinical history of two negative rt-
PCR; hospitalized for more than 15 days; admitted to the ICU and submitted to
mechanical ventilation, who were submitted to a rehabilitation program where the
progression of the aerobic exercise intensities was adjusted according to the patients'
effort tolerance and the resistance exercises lasted from 10 to 15 minutes and were
composed by exercises that use body weight or with the aid of external loads
(washers, dumbbells or elastic bands) . The following measurement instruments were
used: 6MWT, TUG , Hand Grip Test , 60-second Sitting and Standing Test, IPAQ and
SF-36. The patients had pre-existing comorbidities, in which a significant
improvement was identified in markers related to cardiorespiratory physical of 6MWT
Distance (p<0,00), and in the heart rate achieved in the same test (p=0.018),
improvement in TUG (p <0,00), in the sit and stand test with an increase of 9
executions (p<0), in the upper limb strength test (p<0,00), in the quality of life aspects
of Functional Capacity, Pain, General Health Status and social aspects did not show
significant differences, but in the aspects of quality of life related to Limitations due to
Physical Aspects (p=0.005), Vitality (p=0.001), Limitations due to Emotional Aspects
(p=0.012) and Mental Health (p=0.014) a significant improvement was identified,
although the domain of functional capacity did not show a significant difference
(p=0.362), any improvement in this aspect can be considered a clinically significant
improvement. Finally, it is concluded that the physical rehabilitation program
promoted improvements in physical fitness and quality of life of hospitalized patients.

Introduction:Adhesives play an important role in health services as they address many needs, however, adherence to the adhesive base of the colostomy bag has been reported as one of the main problems in the treatment of ostomy patients. Complications such as leaks, dermatitis, skin lesions may be related to poor adhesiveness. Based on this principle, studying the adhesion of the adhesive bases of colostomy bags from the 3 main companies in the field becomes essential for solving such problems to the health of ostomy patients. Objective: To analyze in vitro the microshear resistance of the adhesion of colostomy bags. Methodology: Descriptive and exploratory research, with a quantitative approach, where 54 specimens from different regions of the adhesive base (periphery, medial and central) were made and submitted to the microshear test, in order to quantify the adhesion force exerted until the detachment of the adhesive base. Such specimens are 0.5X0.5mm² in size and were divided into 3 groups, according to the adhesion time of the adhesive on a previously prepared silicone plate. The test performance time was 60, 120 and 240 min. The data obtained were cataloged and analyzed by IBM SPSS Statistics systems; had normality measured by the Shapiro-Wilk test and to check variables the ANOVA One-way test. Results: In this experiment, after carrying out the microshear test, it was noticed that there was no statistical significance in any of the studied variables: a) region of the adhesive base; b) mark of the colostomy bag and c) time to perform the test. Thus, the results accept the null hypothesis, in which there was no statistical difference in adhesion strength. Conclusions: The fact that they have the same membership equates the scholarships to the same level of membership. New research must be carried out, both in vitro and in vivo, to better detail the adhesive properties of colostomy bags.

Obesity and overweight are a growing public health problem, current treatments are
based on nutritional approaches and behavioral changes, but weight regain rates in
this population are still high. Factors such as difficulties in emotional regulation and in
some executive functions influence the eating pattern adopted by this population.
Given the above, this research evaluated the effectiveness of an intervention based
on Cognitive Behavioral Group Therapy (CBT) in conjunction with computerized
training for executive function in obese and overweight individuals. It is also intended
to evaluate the correlation between emotional dysregulation, impulsivity and eating
patterns. The intervention has a convenience sample, consisting of 18 participants
randomly divided into a control group and an experimental group. Data collection was
carried out using the following scales: Tree Factor Eating Questionnaire (TFEQ-R21),
to assess eating behavior, Difficulties in Emotional Regulation Scale (DERS) to assess
difficulties in emotional regulation; Impulsivity Rating Scale (ESAVI), to assess
impulsivity. The results found indicated that, regardless of the group, changes occurred
in the evaluated domains. A positive correlation was found in the experimental group
between emotional eating and emotional dysregulation. The intervention associating
CBT for emotional regulation with executive functions training did not prove to be
superior to the intervention applied alone. The findings of this study support the
hypotheses of the association between difficulties in eating behavior and emotional
regulation and that therapeutic interventions based on behavioral change and
emotional regulation can enable improvements in eating behavior.

OBJECTIVE: The aim of this study was to analyze the effects of sunflower oil
supplementation with pancreatic cell conditioned medium on Alzheimer-induced cortical
neurons. MATERIAL AND METHOD: Nerve cortical cells were collected from newborn
Wistar rats, the acquisition of the pancreas was from an adult Wistar rat and the beta-amyloid
peptide, which has the ability to induce alzheimer's, was diluted in double distilled water,
having then been cultivated in different groups, a control (D-10) and the others with different
groups (OG, βA, MCP) with cellular morphology evaluated at the end of 96 hours. Cell
expansion data (area, perimeter and axonal length) at 96 hours were statistically compared
using the Kruskal-Wallis test in multiple pairwise comparisons, being considered significant
when p<0.05. RESULT: At the end of 96 hours it was verified that the culture of cells when
cultivated in G7 (D-10, βA, OG) and G8 (MCP, βA, OG) presented morphometric alterations
when compared to the other groups (G2,G3,G4,G5,G6) without joint treatment of MCP and
OG, thus allowing a more evident identification of the morphology of glial and neuronal cells,
resulting in the plastic effect. CONCLUSIONS: Experimental groups treated with GO alone
and in combination with MCP, in the midst of βA showed more pronounced changes when
compared to the control group (D-10), mainly in G7 and G8. Thus, it is shown that OG and
MCP act in neuroprotection, neuroregeneration, acting in the reduction of aggregated
beta-amyloid senile plaques, important for possible treatments of neurodegenerative disorders
such as AD.

Introduction: The use of mobile technology has become increasingly necessary in
contemporary society, causing negative and positive effects on users, in the health
area, for example, identifying, tracking and treating conditions early in individuals can
be decisive for any and all. clinical condition. Objective: Create and validate a free
mobile application that assesses common mental disorders and meaning of life, with
educational information about these constructs, in order to meet the needs of users
by promoting health and education. Methodology: The study was divided into three
stages: the 1st (first) stage included the creation of the application's content, the
design process and programming. In the 2nd (second) stage, the application was
evaluated by specialists in the field of psychological assessment and clinical
psychology, in the area of technology. In the 3rd (third) and last stage, the pilot study
will take place. For the pilot study, snowball sampling was used, which is a form of
non-probabilistic sampling. Due to this type of sampling, a period of time for data
collection was stipulated, between April 24, 2023 and May 24, 2023. Results:
ConheSer was conceived from two words: Knowing and Being, in the expectation
that the subject can self-know in order to be who he is, based on a phenomenological
reading. For Design, the Figma tool was used, where the user interface and the
prototype were developed. With regard to programming, it was carried out from
NodeJS (Backend, Api), for the Postgresql database and to index the APP from
Flutter. In the programming process, the codification of the previous processes
enters, to generate the application. Where I joined the design with the wireframe. The
validation process of the judges, very well qualified (40% Doctors and 60% Masters),
evaluated the educational material as adequate, obtaining a score of 0.88 on the
CVI, as well as adequate for the public, scoring 86 on the SAM. Evaluating the
application in general, the judges understood, based on the Kappa coefficient, that
the application is suitable for the objectives, where it obtained a score of 90, meaning
adequacy. After the validation of the judges, the pilot study took place, where it was
possible to see the stability of the application, remaining stable and storing the data
correctly. In addition, information was collected on how users see the usability of the
application from the 52 participants, 76.9% rated it as best imaginable and 100% of
these classified it between best imaginable, excellent and good, understanding from
the SUS parameters that the application is usual. Conclusion: This research
highlighted the creation and validation processes of a mobile application, aimed at
promoting mental health and health education. It is noticeable from the evaluation of
the judges that the application has the potential for what it was designed for, in all
evaluations it obtained excellent scores.

People with rare genetic diseases (RGDs) face a series of challenges in monitoring
their condition, from birth to diagnosis and treatment, the whole routine is changed and
situations of great anguish and suffering plague patients and their families. Therefore, the
present study aimed to investigate the impact of access to health and social support, on the
population with rare genetic diseases, caused by the Covid-19 pandemic. With regard to
methodology, it is a descriptive observational cross-sectional study that falls within the scope
of quali-quantitative research. The fields of study will be: Hospital Regional Dr. Tarcísio
Vasconcelos Maia – HRTM; Mossoroense League of Studies and Fight against Cancer –
LMECC; Hemotherapy and/or Hematology Care Center of Mossoró – HEMOCENTRO;
Central Unit of Therapeutic Agents – UNICAT; and DGR's Association of Rio Grande do
Norte. The interest and choice of these sites was due to the fact that they represent a reference
for the treatment/support of patients with DGR's. Inclusion Criteria: Having a confirmed
diagnosis for any type of Rare Genetic Disease (over 18 years old), or being the legal guardian
of the patient (if under 18 years old or legally incapable); A guardian must be present at the
time of the interview, if minors or children. Exclusion criteria: Patients with a suspected Rare
Genetic Disease, but the diagnosis is not completely closed; Cognitive inability of the
interviewee (patient or caregiver) to understand the instrument's questions. To carry out the
data collection, the instrument “Perception Scale of Access to Health and Social Support for
people affected by Rare Diseases (Passs)”, calibrated and validated (Salviano et al., 2020),
was used. The instrument comprises four domains with a total of 38 items, namely: 08 items
from Health Resources, 07 items from Financial Resources, 13 items from Social Aspects and
10 items from Individual Aspects. 152 patients with DGR's were analyzed, 90 men and 62
women. Regarding the sociodemographic characteristics of the patients, individuals aged 5 to
18 years (88-57.9%), with incomplete primary education (71-46.7%) and from Natal (47-
31.9%) and region predominated. metropolitan area of Natal (47- 31.9%). The most
expressive family income was 1 to 2 salaries (102-70%) (Table 1), which is understandable,
since the vast majority of caregivers have a low level of education or are illiterate. The main
genetic diseases found in this study were neuromuscular DGR's: Muscular Dystrophies with
46 cases, mostly Duchenne, followed by 23 cases of Spinal Muscular Amyotrophy types 1,2,3
and Mucopolysaccharidosis types 1,4,6 with 19 cases. The survey results show reasonably
adequate support, health resources and social aspects are above average and financial
resources were regular. However, individual aspects were compromised and, as a
consequence of the Covid-19 pandemic, there were interruptions, cancellations and
postponements in the treatment of patients, with teleconsultation and/or online monitoring
being fundamental actions for good care. Thus, it is necessary to constantly improve strategies
for valuing and improving the National Policy for Comprehensive Care for people with DGR,
aiming to contribute to a more effective network of health services.

This study aims to cross-culturally adapt the “Holistic Assessment” instrument from the tide model for use in Brazil. As a result of this, objectively: investigate the semantic, idiomatic, conceptual and cultural equivalences of the “Holistic Assessment” adapted for Brazil through a committee of experts and verify the evidence related to clearly in the response process of the adapted version of the “Holistic Assessment ” by users and nurses. This is a methodological study of cross-cultural adaptation, following the methodology proposed by Beaton, which consists of 6 stages, namely: Initial translation; Synthesis of translations; Retrotranslation or Back Translation; Review by a committee of experts; Pre-test and submission of the pre-final version to a Scientific Committee specialized in cultural adaptation. Translations and back-translations were carried out independently by 4 bilingual translators. The translation synthesis was carried out by the author and the advisor using standardization and adequacy criteria. The back-translation synthesis was carried out with the help of another translator, by the author and supervisor. Evidence of content validity was obtained through a committee formed by 11 specialist nurses, being verified as semantic, idiomatic, conceptual and cultural equivalences, which were analyzed using the content validity and reliability index. The semantic content analysis of the adapted instrument was carried out through pre-testing with 15 users of the Psychosocial Care Center and 15 nurses from CAPS's and the Family Health Strategy, using the survey method and application of responses through a scale I like. The translation and cultural adaptation stages allowed linguistic adjustments to be made for better understanding and practical applicability of the instrument items for use in Brazil. The content validity index of the Brazilian version was 0.99 and Cronbach's alpha was 0.82. In the pre-test, the average degree of global understanding by users was 4.7 while for nurses it was 4.8. Furthermore, 100% (n=15) of nurses stated that the instrument clearly presents the information, visualizes its practical applicability and would use it in their clinical practice. Therefore, the transcultural adaptation of the instrument was carried out, thus enabling the availability of the holistic assessment instrument to be used in nurses' clinical practice in mental health care in Brazil. The study has the potential to contribute to the advancement of scientific knowledge in the area of health and nursing, qualifying nurses' assistance in mental health care in Brazil through practices based on technical/scientific knowledge and based on knowledge specific to the profession, such as the use of nursing theories, including the Tidal Model and this Holistic Assessment instrument.

The objective is to evaluate the performance of Community Health Agents (ACS) in the face of the Covid-19 pandemic, at the level of Primary Health Care (PHC), in the municipality of Apodi, Rio Grande do Norte, Brazil. The specific objectives are: to know the challenges faced by the ACS for the development of their work in the context of the Covid-19 pandemic; survey the health activities carried out by the ACS in the context of the Covid-19 pandemic; know the working conditions (infrastructure, training, biosafety guarantee) available for the ACS to act in the context of the Covid-19 pandemic; identify the strategies made possible by the ACS for the development of its work process in the context of the Covid-19 pandemic; and to identify, in the view of the ACS, the strategies made possible by the local management of PHC for the development of its work in the context of the Covid-19 pandemic. This is a descriptive, exploratory research with a qualitative approach. The Basic Health Units (UBS) of Apodi/RN were configured as the research site, which has 11 Family Health Teams (ESF). The research participants were 58 Community Health Agents, from a universe n=83, working in these UBS. Data collection took place through semi-structured interviews that were analyzed using Bardin's Content Analysis (CA) technique. From the analysis, four thematic categories emerged that make up the research results: The potential contribution of ACS in the Covid-19 pandemic; Challenges and difficulties encountered by ACS to carry out their work in the Covid-19 pandemic; Strategies of Local Health Management to face Covid-19 from the perspective of the ACS; and Covid-19 Pandemic Control Measures under the eyes of the ACS. From the results found, we conclude that the reality apprehended, analyzing the perception of the ACS, acting in the pandemic context, corroborates the inexistence of management actions in local health that give support to these professionals with regard to planning, training, activities, that would enable its performance in the context of the Covid-19 pandemic. We realize the importance of a strengthened and structured PHC, being the main gateway of the health sector to epidemic situations such as we experience in this health crisis, since the diversity of attributions such as information on the territory, the strengthening of the bond between the user, family and the health team, comprehensive care, monitoring of vulnerable families and follow-up to cases during home visits and health education, which represent, in this case, important strategies to reduce the implications of a health crisis. Finally, we also concluded that the Covid-19 pandemic demanded a reorganization of the work process and care flows, and for the ACS to continue developing its activities, decent working conditions, training and permanent education must be guaranteed.